Cosmelan and Dermamelan


Melasma and hyperpigmentation have historically been some of the toughest skin conditions to treat because discoloration lies so deep within the skin’s layers and is hard for medications to target. However, with Cosmelan and Dermamelan, these conditions can be greatly improved.

Cosmelan and Dermamelan are depigmentation agents which act by decreasing melanin from the skin. Melanin is responsible for the darkening of the skin and contributing to such factors as melasma and other skin discolorations. Melanin is increased by sun exposure, acne, aging, and hormone fluctuation.

Cosmelan and Dermamelan have the ability to inhibit an enzyme (tyrosinase) that is involved in the process of causing skin darkening. Cosmelan and Dermamelan lead to a decrease in melanin synthesis and hence to a decrease in darkened skin color. Studies have shown that Cosmelan and Dermamelan can effectively reduce skin discolorations by up to 90% if used appropriately.

Cosmelan and Dermamelan treatments are compounded prescription medications that contain an in-office peel application and home care products.

Following the treatment, you should expect some peeling and flaking of the skin. Make-up can be applied daily and light moisturizers and sunscreens should be used throughout the treatment.

No glycolic peels or other lightening agents should be used while you are using Cosmelan or Dermamelan. You should not experience pain, but some stinging and pinkness of the skin can be expected, particularly at night when the home care products are used.

During the two weeks and post-treatment, you will notice a lightening of the treated discoloration and a “breaking up” of the melanin. These results will increase over time. You should use daily sunscreen and can purchase additional home care products, to help keep the melanin from reappearing or developing new areas of pigmentation. If needed, additional full Cosmelan or Dermamelan treatments can be performed.